Laura N. van der Laan,Lisette Charbonnier, Sanne Griffioen-Roose, Floor M. Kroese, Inge van Rijn, Paul A.M. Smeets,
Biological Psychology 117 (2016) 108–116
Restrained eaters do not eat less than their unrestrained counterparts. Proposed underlying mechanismsare that restrained eaters are more reward sensitive and that they have worse inhibitory control. AlthoughfMRI studies assessed these mechanisms, it is unknown how brain anatomy relates to dietary restraint.Voxel-based morphometry was performed on anatomical scans from 155 normal-weight females toinvestigate how regional grey matter volume correlates with restraint. A positive correlation was foundin several areas, including the parahippocampal gyrus, hippocampus, striatum and the amygdala (bilat-erally, p < 0.05, corrected). A negative correlation was found in several areas, including the inferior frontalgyrus, superior frontal gyrus, supplementary motor area, middle cingulate cortex and precentral gyrus(p < 0.05, corrected). That higher restraint relates to higher grey matter volume in reward-related areasand lower grey matter volume in regions involved in inhibition, provides a neuroanatomical underpinningof theories relating restraint to increased reward sensitivity and reduced inhibitory capacity.